Genomics Resources Core Facility

Our Story and Mission

The Genomics Resources Core Facility (GRCF) at WCM, established in 2000, plays a pivotal role in advancing genomics research both internally and externally. It offers a comprehensive range of services from experimental design and sample preparation to instrumentation, data analysis, interpretation, and validation.

At the core of its operations are cutting-edge sequencing technologies and a team of well-trained staff, enabling researchers to leverage state-of-the-art technologies effectively. These resources have not only supported but significantly contributed to numerous publications and successful grant applications within the research community.

The mission of the GRCF is clear: to provide access to high-quality genomics services at affordable costs, thereby fostering innovation and collaboration across the research landscape. By maintaining a commitment to excellence in service delivery and cost-effectiveness, the facility continues to play a critical role in advancing genomic research and its applications.

Our Services

Consultation

To provide options and recommend the optimal experimental strategy.

Sample Quality Control

Including quality and quantity measurement.

Library Construction (Manual or Robot)

  • For DNA: whole genome sequencing, whole exome sequencing, PCR amplicon, Metagenomics, ChIP-Seq, targeted sequencing (panel), sequencing for CRISPR screening.

  • For RNA: whole transcriptome sequencing, capture-based RNA-Seq, miRNA-Seq.

Single-cell Sample Preparation and Sequencing

  • - Single-cell 3' Library RNA-Seq Assays (GEM-X v4 kit)

  • - Single-cell 5' Library RNA-Seq Assays (GEM-X v3 kit)

  • - Single Cell Multiome ATAC + Gene Expression

  • - Single Cell ATAC-Seq

  • - Cell Multiplexing Library Construction (Additional to Single-cell 3' Lib prep)

  • - Single Cell Human TCR / BCR Enrichment (Additional to Single-cell 5' Lib prep)

  • - CRISPR Screening Library Construction (Additional to Single-cell 3' Lib prep)

Sequencing

  • - Illumina sequencing systems – NovaSeq X Plus, NextSeq2000, NextSeq500, MiSeq

  • - PacBio sequencing system - Revio

  • Spatial Nanostring GeoMx: NGS Readout Library Prep.

  • Genomics data storage, management, and bioinformatics support: including primary, secondary and tertiary data analysis, data storage and management.

  • Other support: offering support letter and writing genomics part for PIs’ grant and manuscript preparations.

Schedule your appointment

iLab system: For user registration, sample submission, tracking and billing- iLabs Link


Contact Us

Jenny Xiang, M.D.

Email: jzx2002@med.cornell.edu

Phone:

(212) 746-4258 (O)

(212) 746-6238/5076 (Lab)